Accurate level measurement in complex conditions
Reliable technologies adapted to challenging bioreactor conditions
Level measurement in bioreactors is one of the most important parameters for proper process automation. The liquid level has to be monitored and headspace controlled. The foam built up by aeration and stirring should not penetrate the venting line and block the filters. Moreover, the reactor size, temperature shocks (due to CIP-SIP phases) and changing liquid density are important aspects to consider when selecting the appropriate device or measurement principle.
Various technologies for level measurement
In advanced fermenter applications, radar, guided wave radar or hydrostatic measurements are most common.
However, different parameters must be taken into consideration as they directly influence the technology to select for level measurement:
Size of vessels
Presence or absence of foam
We usually recommend guided wave radar for small vessels, and hydrostatic measurement with fast temperature compensation for larger ones.
Multiple parameters to consider for proper engineering
Tank size and shape
Agitator location, design and speed
Drainability and cleanability
Robustness of sensor
Pipe and process connections
Temperature and pressure shocks
Spray ball design and operations conditions
Media density or viscosity